Nature Unknown label
Credit hour 3
Total number of hours 29
Number of hours for lectures 18
Number of hours for tutorials 10
Number of hours for laboratory work 1

Prerequisites

Fundamentals of physiology, biochemistry, molecular biology, metabolism and nutrition

Goals

? Digestion, storage, and functions of nutrients in growth, development, and aging. ? The role of nutrition in immune function and maintenance of optimal health. ? Cellular mechanisms underlying the harmful effects of sedentary lifestyles. ? Intermediary metabolism and the role of metabolites and signaling molecules in metabolic control and inter-organ communication (muscle, liver, adipose tissue, cardiovascular system, brain) in various physiological states (fed, fasted, starved, exercised). ? Principles of chrononutrition, from intracellular biochemistry to whole-body physiology, focusing on circadian clocks and their impact on metabolic health.

Content

This course introduces the science, applications, and consequences of food choices and lifestyle on human nutritional health. It aims to deepen understanding of the physiological mechanisms underlying metabolic health and disease, providing the basis for designing and optimizing preventive and therapeutic nutritional and lifestyle interventions. The course also emphasizes core skills for nutritionists, including body composition assessment, data generation, statistical analysis, and interpretation.

Lectures:
? Research Skills in Nutrition (3h): Anthropometry – tools for measuring body composition at individual and population levels; strengths and limitations; practical applications in laboratory and dietary assessment.
? Physiology (15h): Energy extraction from macronutrients (carbohydrates, fats, proteins); intermediary metabolism; mitochondrial dynamics; nutritional immunity; chrononutrition; impact of lifestyle interventions (sedentary behavior, sleep, stress) and personalized strategies for health promotion.
Tutorials (12h):
? Overview sessions based on scientific papers; active participation and presentations required.
Fieldwork (1.5h):
? Visit to the Nutritional Exploration Unit at CRNH Auvergne.

Additional Information

? Digestion, storage, and functions of nutrients in growth, development, and aging. ? The role of nutrition in immune function and maintenance of optimal health. ? Cellular mechanisms underlying the harmful effects of sedentary lifestyles. ? Intermediary metabolism and the role of metabolites and signaling molecules in metabolic control and inter-organ communication (muscle, liver, adipose tissue, cardiovascular system, brain) in various physiological states (fed, fasted, starved, exercised). ? Principles of chrononutrition, from intracellular biochemistry to whole-body physiology, focusing on circadian clocks and their impact on metabolic health.