Goals
? Understanding of common mechanisms linking chronic diseases to loss of locomotor capacity and nutritional status.
? Insight into the impact of mobility loss on the onset and progression of chronic metabolic and organ diseases.
? Ability to apply fundamental and technological concepts to analyze associations between nutrition, mobility, and chronic diseases.
? Knowledge of techniques and methods for assessing mobility and dysmobility in patients.
Content
This course provides advanced knowledge in nutrition, locomotor function, and their interrelationships with chronic diseases. It addresses the mechanisms underlying dysmobility, its causes, and its consequences for patients, integrating concepts from nutrition science, physiology, and clinical research.
Lectures
EC1: Diet, Nutrition, Locomotor Activity and Chronic Metabolic Diseases
? Common mechanisms of chronic disease-related dysmobility: inflammation, oxidative stress, insulin resistance, anabolic resistance, energy homeostasis.
? Mobility limitations and their association with nutrition in type 2 diabetes, obesity, cancer, rheumatoid diseases, sarcopenia, osteoporosis, liver diseases (steatosis).
EC2: Diet, Nutrition, Locomotor Activity and Chronic Organ Diseases
? Assessment of mobility in patients with chronic diseases: methods and rationale.
? Main techniques for functional mobility evaluation: gait, balance, mobility indexes (SPPB, hand grip), mobility measures.
? Interest and limitations of mobility assessment; links with morbidity and mortality.
? Biomarkers of dysmobility.
? Mobility limitations and their association with nutrition in cardiac failure, stroke, cardiovascular diseases, chronic kidney disease, pulmonary diseases (COPD), inflammatory bowel diseases, neurodegenerative diseases.
Tutorials
? Analysis of scientific publications.
? Visit to mobility and metabolism exploration platforms.
Additional Information
? Understanding of common mechanisms linking chronic diseases to loss of locomotor capacity and nutritional status.
? Insight into the impact of mobility loss on the onset and progression of chronic metabolic and organ diseases.
? Ability to apply fundamental and technological concepts to analyze associations between nutrition, mobility, and chronic diseases.
? Knowledge of techniques and methods for assessing mobility and dysmobility in patients.
